Table 4 Comparison of serum lactate parameters between the developed hypomagnesemia and non-hypomagnesemia groups

Day 2

Developed HypoMg

N = 37

Non-HypoMg

N = 586

P-value

Lactate level on ICU admission, mmol/L

3.7 (2.4–5.8)

2.0 (1.3–3.1)

 < 0.001

Lactate level on day 2, mmol/L

2.1 (1.1–3.5)

1.4 (1.0–2.1)

0.003

Lactic acidosis on day 2, %

20 (54.1)

154 (26.3)

 < 0.001

Severe lactic acidosis on day 2, %

6 (16.2)

43 (7.3)

0.052

Lactate clearance, %

28.9 (8.2–55.3)

21.4 (0–44)

0.07

Day 3

Developed HypoMg

N = 28

Non-HypoMg

N = 553

P-value

Lactate level on ICU admission, mmol/L

3.0 (2.2–4.0)

2.0 (1.3–3.2)

0.007

Lactate level on day 3, mmol/L

1.7 (1.2–2.6)

1.3 (1.0–1.8)

0.012

Lactic acidosis on day 3, %

10 (35.7)

95 (17.2)

0.013

Severe lactic acidosis on day 3, %

4 (14.3)

14 (2.5)

 < 0.001

Lactate clearance, %

34.7 (17.5–58.5)

34.5 (8.3–56.8)

0.61