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Table 3 Time from administration of reversal agents to recovery of TOFR to 0.7, 0.8, 0.9, and 1.0

From: Decurarization After Thoracic Anesthesia using sugammadex compared to neostigmine (DATA trial): a multicenter randomized double-blinded controlled trial

 

Neostigmine group (n = 34)

Sugammadex group (n = 36)

p-value

Primary endpoint

   

 Recovery of TOFR to 0.9

  Number of patients

34 (100%)

36 (100%)

 

  Median [IQR], s

278 [180–532]

88 [46–145]

 < 0.001

Secondary endpoints

 Recovery of TOFR to 0.7

  Number of patients

30 (88.2%)

29 (80.6%)

 

  Median [IQR], s

149 [102–304]

55 [33–76]

 < 0.001

Recovery of TOFR to 0.8

 Number of patients

30 (88.2%)

27 (75.0%)

 

 Median [IQR], s

195 [119–380]

80 [44–109]

 < 0.001

Recovery of TOFR to 1.0

 Number of patients

18 (52.9%)

31 (86.1%)

 

 Median [IQR], s

358 [220–514]

121 [81–192]

 < 0.001

 Recovery of TOFR to 0.9 within 5 min from reversal administration

20 (58.8%)

34 (94.4%)

 < 0.001

 Recovery of TOFR to 0.9 within 10 min from reversal administration

28 (76.5%)

36 (100%)

0.002

 Recovery of TOFR to 1.0 within 10 min from reversal administration

20 (64.5%)

36 (100%)

 < 0.001

Time to extubation

 Median [IQR], min

17.3 [11–34]

11.7 [8–15]

0.011

 Time to discharge to the ward

 Median [IQR], min

91 [64109]

94 [77–110]

0.572

  1. Data expressed as median [IQR] or number (%)