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Table 3 Perioperative management for cryobulinemic patients

From: Cryoglobulinemia: the “cold” problem in cardiac surgery, a single-center experience and a literature review

Cardiopulmonary bypass and cardioplegia management strategies for cryoglobulinemia

Preoperative management

 -Plasmapheresis and/or plasma exchange [30, 32,33,34,35]

 -Immunosuppressive therapy [30, 32, 34]

 -Steroids [30, 32,33,34,35]

Intraoperative management

 -Warm/cold blood cardioplegia and systemic warming [31,32,33, 35]

 -Warm/cold blood cardioplegia and mild hypothermia (temperature above cryoprecipitation threshold) [28, 34]

 -Hypothermia after negative cryo test [30]