From: Cryoglobulinemia: the “cold” problem in cardiac surgery, a single-center experience and a literature review
Type
Characteristic
Single type cryoglobulins (SC)
Type I
Monoclonal
IgM, IgG, rarely IgA
Mixed type cryoglobulins (MC)
Type II
IgM(k) with rheumatoid factor activity
Type III
Policlonal
IgM–IgG immunocomplexes