Skip to main content

Table 1 Details of block procedure and analgesic regimens in the included RCTs

From: Analgesic efficacy and safety of erector spinae versus serratus anterior plane block in thoracic surgery: a systematic review and meta-analysis of randomized controlled trials

Author/Year

Preincisional analgesia and anti-emetics

Block timing

ESPB local anesthetic bolus

SAPB local anesthetic bolus

Localization

Supplemental postoperative analgesia

Gaballah (2019) [25]

Lidocaine 1% (5 ml/port site)

Preoperative (after GA)

20 mL of 0.25% bupivacaine

20 ml of 0.25% bupivacaine superficial to SAM

USG

If VAS ≥ 4, IV ketorolac 30 mg, IV pethidine 0.5 mg/kg prn

Finnerty (2020) [12]

Paracetamol 1 g, IV and dexketoprofen 50 mg, ondansetron 0.1 mg /kg, Dex 0.1 mg/kg

Preoperative (after GA)

30 ml of 0.25% Levobupivacaine in

levobupivacaine 0.25% in 30 ml volume deep to the SAM

USG

Oxycodone 2 mg IV until VAS ≤ 2, paracetamol 1 g IV 6 hourly, ibuprofen 400 mg orally eight hourly, ondansetron 4 mg PO/IV q8h

Ekinci (2020) [15]

-

Preoperative (before GA)

20 mL volume of 0.25% bupivacaine

20-mL volume of 0.25% bupivacaine deep to SAM

USG

400 mg ibuprofen and a 100 mg tramadol IV immediately after the procedure, ibuprofen 400 mg IV q8h, PCA 2 ml of 10-mg/mL fentanyl, lockout time of 20 min, meperidine (0.5 mg/kg) IV if VAS ≥ 4

Elsabeeny (2021) [24]

1 g paracetamol IV infusion

Preoperative, single shot (after GA) followed by continuous infusion for 24 h postoperatively

30 mL of 0.25% bupivacaine followed by continuous infusion of 0.125% bupivacaine at a rate of 8–10 mL/h

30 mL of 0.25% bupivacaine deep to SAM, followed by continuous infusion of 0.125% bupivacaine at the rate of 8–10 mL/h

USG

1 g paracetamol IV infusion q8h, if VAS < 4, IV 30 mg ketorolac given; if VAS ≥ 4, IV morphine with a maximum dose of 0.1 mg/kg

Hassan (2022) [7]

-

Preoperative (before GA)

20 ml of 0.5% bupivacaine

20 ml of 0.5% bupivacaine superficial to SAM

USG

PCIA: 1 mg morphine of 1 mg/ml solution lockout interval of 10 min

Zengin 2022 [26]

IV 50 mg dexketoprofen, 100 mg tramadol

Preoperative (after GA)

20 mL of 0.25% bupivacaine

10 mL of 0.25% bupivacaine deep and superficial to SAM

USG

PCIA: 1 mg morphine with a lockout interval of 15 min. IV 1 g paracetamol q8h, 50 mg dexketoprofen twice daily

Zhang (2022) [27]

IV sufentanil 0.5 μg/kg

Preoperative (after GA)

20 mL of 0.4% ropivacaine

20 mL of 0.4% ropivacaine deep to SAM

USG

PCIA: 150 μg sufentanil with a loading dose of 2 mL, background dose of 2 mL, and locking duration of 15 min. IV 40 mg parecoxib sodium until NRS ≤ 3

Das (2022) [28]

-

Preoperative (before GA)

30 mL of LA mixture (bupivacaine 0.5% and 2% lignocaine with adrenaline 1:100,000)

30 mL of LA mixture (bupivacaine 0.5% and 2% lignocaine with adrenaline 1:100,000) superficial to SAM

USG

PCIA: 0.5 μg/kg fentanyl

Taha (20,230 [23]

-

Preoperative (after GA)

20 mL of 0.25% bupivacaine

20 mL of 0.25% bupivacaine superficial to SAM

USG

IV 1 g paracetamol q8h for the first 24 h, if VAS ≥ 3, IV pethidine 25 mg with maximum dose 150 mg/day

  1. GA general anesthesia, ESPB erector spinae plane block, SAPB serratus anterior plane block, LA local anesthetic, USG ultrasound-guided, IV intravenous, q every, prn as needed, PCIA patient-controlled intravenous analgesia, SAM serratus anterior muscle, VAS visual analog scale, Dex dexamethasone.