Subclinical cardiac dysfunction may impact on fluid and vasopressor administration during early resuscitation of septic shock

Table 3 Therapeutical approach to early resuscitation

Patients–no. (%)	Cardiac dysfunction (CFI ≤ 4.5 min⁻¹) 17 (42)	Normal cardiac function (CFI > 4.5 min⁻¹) 23 (58)
Crystalloids (mL/kg PBW)	57 ± 10	47 ± 9 ^#
N. of patients treated with crystalloids	17	23
Norepinephrine (mcg/kg/min)	0.65 ± 0.25	0.43 ± 0.29 *
N. of patients treated with norepinephrine	17	23

Data are expressed as mean ± standard deviation or median [Interquartile range], as appropriate
^*p < 0.05 compared to the cardiac dysfunction group
^#p < 0.01 compared to the cardiac dysfunction group
Abbreviations: CFI Cardiac function index, PBW Predicted body weight

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