Subclinical cardiac dysfunction may impact on fluid and vasopressor administration during early resuscitation of septic shock

Table 1 Demographical and clinical characteristics of the patients

	Cardiac dysfunction (CFI ≤ 4.5 min⁻¹)	Normal cardiac function (CFI > 4.5 min⁻¹)	p (t test)	p (exact Fisher-test)
Patients—no. (%)	17 (42)	23 (58)
Age—year	57.5 ± 12.5	56.6 ± 11.6	0.680
Male sex—no. (%)	11 (65)	13 (57)		0.747
Height—cm.	169.1 ± 11.1	170 ± 9.8	0.667
Kg PBW	63.9 ± 10.8	65.6 ± 8.9	0.379
BMI	27.6 ± 2.4	27.1 ± 4.6	0.440
SAPS II	34 [30.8–37.8]	28 [24.5–37.5]	0.128
Hemoglobin—g/dL	11.1 ± 3.0	11.2 ± 2.6	0.895
Creatinine—mg/dL	1.3 [0.9–2.3]	1.1 [0.8–1.6]	0.208
Bilirubin—mg/dL	0.8 [0.6–2.3]	0.8 [0.5–1.6]	0.722
SOFA score	8 [8-10]	8 [6.5–9.5]	0.411
Days before ICU admission	2.7 ± 1.5	3.2 ± 1.5		0.28
30 days mortality—no. (%)	12 (71)	9 (39)		0.062
Site of Infection—no. (%)
Respiratory	9 (53)	14 (61)		0.898
Abdominal	4 (23)	5 (22)
Genitourinary	1 (6)	0 (0)
Bacteremia, site unspecified	3 (18)	4 (17)

Data are expressed as as mean ± standard deviation or median [interquartile range], as appropriate
Abbreviations: CFI Cardiac function index, PBW Predicted body weight, calculated as follows: for men, 50 + 0.91 (height in centimeters 152.4); and for women, 45.5 + 0.91 (height in centimeters 152.4), BMI Body mass index, calculated as the weight in kilograms divided by the square of the height in meters, SAPS II Simplified Acute Physiology Score, SOFA Sequential Organ Failure Score

ISSN: 2731-3786