Table 4 Medications given 48 h before extubation among critically ill patients with intellectual disability versus matched patients without intellectual disability
Study group (n = 58) | Modified controls (n = 116) | p value vs. modified controls | 95% CI | |
|---|---|---|---|---|
Total number of drugs given within 0–48 h prior to extubation. Mean ±SD [median; IQR; min–max] | 2.8 ± 1.1 [12; 2–4; 1–6] | 3.2 ± 1.5 [12; 2–4; 1–6] | 0.192 | − 0.06, 0.2 |
Propofol % (n) | 56% (28) | 77.6% (38) | 0.023 | 0.02, 0.56 |
Midazolam % (n) | 10% (5) | 22.4% (11) | 0.092 | − 0.06, 0.35 |
Dexmedetomidine % (n) | 8% (4) | 6.1% (3) | 1 | 0, 0 |
Morphine % (n) | 8% (4) | 20.4% (10) | 0.076 | − 0.07–0.35 |
Fentanyl % (n) | 12% (6) | 20.4% (10) | 0.256 | − 0.07, 0.35 |
Remifentanil % (n) | 40% (20) | 44.9% (22) | 0.622 | − 0.07, 0.35 |
Ketamine % (n) | 0% (0) | 1% (2) | 0.495 | 0, 0 |
Methadone % (n) | 14% (7) | 22.4% (11) | 0.276 | 0, 0 |
Seroquel % (n) | 8% (4) | 18.4% (9) | 0.127 | 0, 0 |
Clonex % (n) | 6% (3) | 24.5% (12) | 0.010 | 0, 0 |
Halidaol % (n) | 6% (3) | 16.3% (8) | 0.102 | 0, 0 |
Clozapine % (n) | 4% (2) | 0% (0) | 0.495 | 0.08, 0.22 |