Table 1 Presentation of mean heart rate and mean arterial pressure recordings (mean ± SD) for three different sugammadex dose groups through experiment by intervals. There was no significant statistical difference, except heart rate significantly increased at the 5th min correlating with higher doses
From: Investigation of proarrhythmic effect of high sugammadex doses: an experimental animal study
Group L | Group M | Group H | p | |
|---|---|---|---|---|
Heart rate | ||||
Basal | 156.2 ± 53.7 | 228.4 ± 18.6 | 196.0 ± 41.2 | 0.083 |
5 min | 153.6 ± 26.1 | 191.8 ± 18.8 | 215.2 ± 21.6 | 0.008 |
10 min | 161.2 ± 26.0 | 215.0 ± 23.2 | 198.8 ± 47.2 | 0.100 |
20 min | 167.8 ± 33.2 | 201.4 ± 22.6 | 211.2 ± 33.8 | 0.174 |
25 min | 172.6 ± 18.3 | 204.2 ± 16.5 | 200.6 ± 29.2 | 0.049 |
30 min | 164.2 ± 28.5 | 184.4 ± 27.9 | 200.0 ± 24.4 | 0.222 |
40 min | 164.2 ± 27.5 | 179.4 ± 36.1 | 207.4 ± 31.9 | 0.156 |
Mean arterial pressure | ||||
Basal | 71.8 ± 6.4 | 89.6 ± 21.8 | 78.4 ± 5.6 | 0.364 |
5 min | 66.2 ± 13.1 | 73.8 ± 20.8 | 79.0 ± 18.4 | 0.562 |
10 min | 70.2 ± 1.8 | 63.8 ± 6.7 | 74.6 ± 10.4 | 0.228 |
20 min | 61.6 ± 8.4 | 66.4 ± 9.0 | 69.8 ± 11.3 | 0.578 |
25 min | 64.2 ± 6.6 | 85.8 ± 16.4 | 76.8 ± 10.8 | 0.061 |
30 min | 70.0 ± 11.5 | 86.0 ± 11.9 | 75.6 ± 10.7 | 0.064 |
40 min | 78.4 ± 22.0 | 94.6 ± 13.1 | 83.2 ± 17.5 | 0.402 |