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Table 2 Characteristics of spinal anesthesia in the included studies

From: Spinal anesthesia and hypotensive events in hip fracture surgical repair in elderly patients: a meta-analysis

 

Study

 

Errando et al. [29]

Ben David et al. [30]

Olofsson et al. [31]

Martyr et al. [32]

Kahloul et al. [33]

Lilot et al. [34]

Anesthetic

Hyper

Bupivacaine

0.25%

Hyper

Bupivacaine

0.5%

Hyper

Bupivacaine

0.5%

Hyper

Bupivacaine

0.5%

Hypo

Bupivacaine

0.5%

Hypo

Bupivacaine

0.5%

Iso-hypo ropivacaine

0.75%

Dose (mg)

3.75

7.5

4

10

7.5

15

9

11

5

7.5

6

8

10

12

Subgroup

L

H

L

H

L

H

L

H

L

H

L

L

H

H

Adjuvant (opiate)

N/A

N/A

Fentanyl

N/A

Sufentanil

N/A

Fentanyl

N/A

Fentanyl

Fentanyl

Sufentanil

Sufentanil

Sufentanil

Sufentanil

Adjuvant dose (mcg)

-

-

20

-

5

-

20

-

25

25

5

5

5

5

Puncture level

L2–L3

L3–L4

L2–L3

L3–L4

L3–L4

L3–L4

L2–L3

L2–L3

L3–L4

L3–L4

L3–L4

L4–L5

L3–L4

L4–L5

L3–L4

L4–L5

L3–L4

L4–L5

L3–L4

L4–L5

L3–L4

L4–L5

Needle size

25 G

25 G

22 G

22 G

27 G

27 G

22 G

22 G

-

-

25 G

25 G

25 G

25 G

Infused volume (ml)

1.5

1.5

2

4

-

-

2.2

2.2

3

3

-

-

-

-

Position during procedure

Lateral on the operating side

Lateral on the operating side

Lateral, fracture side up

Lateral, fracture side up

Sitting

Sitting

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Lateral, fracture side up

Level of sensory block (max)

T10

T10

T8

T6

T7

T6

T6–T12

T5–L3

-

-

-

-

-

-

Sensory block onset (min)

-

-

-

-

-

-

-

-

8 (4)

6 (2)

-

-

-

-

Motor block onset (min)

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Duration sensory block (min)

78.6 [60–160]

125.5 [70–210]

-

-

-

-

-

-

91 (32)

113 (19)

105 [100–200]

120 [105–160]

140 [110–160]

133 [108–170]

Duration motor block (min)

-

-

-

-

-

-

-

-

-

-

115 [100–125]

120 [105–131]

150 [110–160]

123 [108–213]

Modified Bromage scale (0–3)

-

-

-

-

2

3

-

-

-

-

-

-

-

-

Type of fluid infused

RL

RL

RL

RL

RL

RL

HaS

HaS

NS

NS

HES

HES

HES

HES

Dose of infused fluid (mg/kg)

-

-

8

8

-

-

8

8

5

5

5

5

5

5

Total fluid administered (ml)

500

500

-

-

500

500

-

-

-

-

-

-

-

-

Patients with hypotensive events (%)

14

76

10

90

16

88

25

75

59

92

53

47

83

81

  1. Hyper hyperbaric, Hypo hypobaric, Iso isobaric, L low-dose subgroup, H high-dose subgroup, N/A not administered, G gauge, RL Ringer Lactate, HaS Hartmann’s solution, NS normal saline, HES hydroxyethyl starch 6%. Bromage motor blockade score: grade I, free movement of legs and feet; grade II, just able to flex knees with free movement of feet; grade III, unable to flex knees, but with free movement of feet; and grade IV, unable to move legs or feet. The fluids infused before spinal anesthesia are reported as either a standardized bolus (i.e., 500 ml for all the enrolled patients) or a weight-based bolus (5–8 ml/hg)