Perioperative goal-directed therapy and postoperative complications in different kind of surgical procedures: an updated meta-analysis

Table 4 Total amount of fluids, colloids, and crystalloids used in all RCTS included

Patients with complications All studies	n. of study (references)	Treatment	Control	Standard mean difference (95%CI)	p value	I²	q statistic p value
Total fluids (ml)	9 (22, 31, 33, 34, 37, 41, 43, 46, 53)	473	484	− 1.14 (− 2.38,0.11)	0.07	98%	p < 0.00001
Colloids (ml)	12 (20–22, 26, 29, 33, 34, 45–47, 53, 56)	796	820	0.71 (0.07, 1.36)	0.003	97%	p < 0.00001
Crystalloids (ml)	12 (20–22, 26, 29, 33, 34, 37, 45–47, 56)	765	786	− 2.07(− 1.03, − 3.11)	0.0001	99%	p < 0.00001

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