Study group (n = 58) | Modified controls (n = 116) | p value | 95% CI | |
---|---|---|---|---|
Proportion of patients intubated (within the full cohort) % (n) | 86.2% (50/58) | 37.9% (44/116) | < 0.001 | 0.77, 0.95 |
Time from intubation to first weaning attempt (days) Mean±SD [median; IQR; min–max] | 4.8 ± 5.04 [1; 1–7.5; 0–23] | 2.7 ± 2.8 [1; 1–4; 0–11] | 0.020 | 0.34, 3.8 |
Time from first weaning attempt to extubation (days) Mean±SD [median; IQR; min–max] | 1.5 ± 2.5 [1; 0–2; 0–14] | 0.48 ± 1.4 [1; 0–1; 0–14] | 0.007 | 0.3, 1.78 |
Intubation duration (days) Mean±SD [median; IQR; min–max] | 7.3 ± 6.2 [5; 2–11; 1–24] | 4.06 ± 2.7 [4; 2–5; 1–12] | 0.005 | 1.05, 5.45 |
Number of extubation attempts Mean ±SD [median; IQR; min–max] | 1.1 ± 0.6 [3; 1–1; 0–3] | 0.9 ± 0.4 [3; 1–1; 0–2] | 0.093 | − 0.03, 0.41 |
Number of weaning attempts Mean±SD [median; IQR; min–max] | 1.19 ± 0.890 [3; 1–2; 0–4] | 0.88 ± 0.498 [3; 1–1; 0–2] | 0.055 | − 0.007, 0.62 |
Number of self extubations Mean ±SD [median; IQR; min–max] | 0.05±0.221 [0; 0-1; 0-1] | 0.06±0.233 [0; 0-1; 0-1] | 0.7801 | -0.01, 0.12 |
Proportion of ultimately successful extubations % (n) | 61.2% (30) | 75.0% (33) | 0.156 | 0.65, 0.9 |
Reintubation within 24 h from extubation % (n) | 5.2% (3) | 3.4% (4) | 0.592 | 0, 0.16 |
Tracheostomy (all patients) % (n) | 20.7% (12) | 2.6% (3) | < 0.001 | − 0.1, 0.13 |
Tracheostomy (intubated patients) % (n) | 24% (12) | 6.1% (3) | 0.013 | − 0.1, 0.13 |