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Table 1 Baseline characteristics of critically ill patients with intellectual disability versus matched patients without intellectual disability

From: Intellectually disabled patients’ intensive care admission characteristics, weaning from mechanical ventilation, and sedative drug use: a single-center retrospective case-control study

 

Study group with control

(n = 174)

Study group

(n = 58)

control

(n = 116)

p value

95% CI

General demographics

Age (years)

Mean±SD

[median; IQR; min–max]

39.5 ± 13.9 [39; 28.8–49.3; 18–70]

39.6 ± 13.9 [39.5; 28.8–49.3; 18–70]

39.4 ± 14 [39; 28.3–49.8 ; 18–70]

Matched

Sex (M/F)

% (n)

67.2%/32.8% (117/57)

67.2%/32.8% (39/19)

67.2%/32.8% (78/38)

Matched

Admitted from (home/institution)

% (n)

78.7/21.3 (137/37)

41.4%/58.6% (24/34)

97.4%/2.6% (113/3)

< 0.001

0.99, 1.04

Severity of acute disease assessment

APACHE II score

Mean±SD

[median; IQR; min–max]

15.1 ± 8.9 [12.5; 8.8–20; 0–44]

18.5 ± 8.7 [18; 11–23.3; 4–44]

13.4 ± 8.5 [12.5; 7–18; 0–43]

< 0.001

11.6, 14.5

Use of vasopressors % (n)

35.1% (61)

51.7% (30)

26.7% (31)

0.001

0.02, 0.56

Use of renal replacement therapy

% (n)

1.2% (2)

1.7% (1)

0.9% (1)

p = 0.615

0, 0

Admission characteristics

Surgical/non-surgical admission

% (n)

44.3%/55.7% (77/97)

37.9%/62.1% (22/36)

47.4%/52.6% (55/61)

0.235

1.35, 1.53

Referring department

% (n)

Internal i

21.8% (38)

22.4% (13)

21.6% (25)

0.213

2.53, 3.07

Surgical ii

17.8% (31)

22.4% (13)

15.5% (18)

Gynecology

6.9% (12)

3.4% (2)

8.6% (10)

Emergency department

39.7% (69)

46.6% (27)

36.2% (42)

Neurosurgery

10.9% (19)

5.2% (3)

13.8% (16)

Unknown

2.9% (5)

0% (0)

4.3% (5)

Cardiovascular disease

% (n)

18.4% (32)

22.4% (13)

16.4% (19)

0.333

0.08, 0.21

Hypertension

% (n)

16.1% (28)

15.5% (9)

16.4% (19)

0.884

0.09, 0.22

Pulmonary disease

% (n)

8% (14)

5.2% (3)

9.5% (11)

0.324

0.02, 0.12

Renal disease

% (n)

6.3% (11)

3.4% (2)

7.8% (9)

0.271

0.03, 0.13

Hematological disease

% (n) iii

13.2% (23)

20.7% (12)

9.5% (11)

0.040

0.02, 0.12

Malignancy

% (n)

12.1% (21)

12.1% (7)

12.1% (14)

1

0.06, 0.18

Endocrinological condition (other than diabetes mellitus)

% (n) iv

16.7% (29)

31.0% (18)

9.5% (11)

< 0.001

0.02, 0.12

Diabetes mellitus

% (n)

19.0% (33)

17.2% (10)

19.8% (23)

0.682

0.12, 0.26

Obesity

% (n) v

14.4% (25)

19.0% (11)

12.1% (14)

0.221

0.03, 0.14

Neurological disease

% (n) vi

24.7% (43)

37.9% (22)

18.1% (21)

0.004

0.09, 0.22

Psychiatric disorders

% (n) vii

19.0% (33)

25.9% (15)

15.5% (18)

0.101

0.08, 0.21

Chronic infectious disease

% (n) viii

8.0% (14)

10.3% (6)

6.9% (8)

0.431

0.02, 0.12

Smoking

% (n)

24.7% (43)

6.9% (4)

33.6% (39)

< 0.001

0.25, 0.42

Other disease

% (n) ix

35.1% (61)

37.9% (22)

33.6% (39)

0.574

0.23, 0.40

  1. iIncludes Hematology-Oncology, Otolaryngology (1 patient–without surgical intervention), Cardiac Intensive Care Unit, Cardiology, Neurology
  2. iiIncludes Otolaryngology/Head and Neck Surgery, Orthopedics, Vascular surgery, Urology
  3. iiiIncludes anemia, polycythemia, thalassemia, coagulation disorders, hematological malignancy
  4. ivIncludes hyper/hypo-thyroidisim, hyper/hypo-parathyroidism, osteoporosis, Addisson disease, polycystic ovary syndrome, Cushing syndrome, panhypopituitirism
  5. vBased on International Clinical Diseases-9 diagnosis code
  6. viNeuromuscular diseases, epilepsy, dementia, stroke, arterio-venous malformation, migranes
  7. viiAutism, schizophrenia, schizo-affective disorder, depression, drug and alcohol abuse
  8. viiiHepatitis B, hepatitis C, HIV, recurrent infections, Carbapenem Rresistent Klabsiella Pneumonia/Vancomycon Resistent Enterococcus carriers
  9. ixRheumatology disorders, inflammatory bowel disease, genetic disorders, underwent major surgeries, allergies, gastrointestinal conditions, immune deficiencies, pregnancy
  10. Statistically significant findings (p ≤ 0.05) are highlighted. The 95% CI refers to the difference between proportions
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Journal of Anesthesia, Analgesia and Critical Care

ISSN: 2731-3786

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