Table 1 Baseline characteristics of source population. Data are presented as mean ± SD for continuous variables normally distributed; percentages are reported for categorical variables
From: Krebs von den Lungen 6 (KL-6) levels in COVID-19 ICU patients are associated with mortality
Variables | Complete sample n = 122 Median values | Group A n = 61 | Group B n = 61 | p |
|---|---|---|---|---|
Age | 67 ± 11 | 67 ± 13 | 68 ± 9 | 0.443 |
Sex: M/F | 31/91 | 15/46 | 16/45 | 0.907 |
Hypertension | 58 (47.5%) | 24 (39.3%) | 34 (55.7%) | 0.102 |
Obesity | 17 (13.9%) | 9 (14.8%) | 8 (13.1%) | 0.794 |
Diabetes | 36 (29.5%) | 20 (32.8%) | 16 (26.2%) | 0.552 |
CV pathologies | 26 (21.3%) | 12 (19.7%) | 14 (23.0%) | 0.825 |
Autoimmune disease | 2 (1.6%) | 1 (1.6%) | 1 (1.6%) | 1.000 |
Malignancies | 6 (4.9%) | 3 (4.9%) | 3 (4.9%) | 1.000 |
Respiratory diseases | 23 (18.9%) | 11 (18.0%) | 12 (19.7%) | 0.817 |
CKD | 4 | 3 | 1 | 0.61 |
Length of stay (ICU days) | 5 [3–9] | 5 [3–9] | 5 [4–8] | 0.31 |
P/F | 126 ± 59 | 146 ± 69 | 108 ± 40 | 0.001 |
SOFA | 5 [3–7] | 4 [3–6] | 6 [4–8] | 0.003 |
WBC day 1 103/mm3 | 9.8 [7.4–13.2] | 9.2 [7–11.8] | 11.5 [8.1–14.3] | 0.169 |
PCT day 1 | 0.15 [0.08–0.71] | 0.11 [ 0.07–0.32] | 0.32 [0.1–1.0] | 0.088 |
SAPS II | 28.0 ± 10.6 | 25.7 ± 11.3 | 30.8 ± 10.3 | 0.02 |
CT scan | 29 | 16 | 13 | |
Lobes involved | 5 [5–5] | 5 [4, 5] | 5 [5–5] | 0.45 |
Consolidations | 22 (76%) | 11 (69%) | 11 (85%) | 0.410 |
Crazy paving | 6 (21%) | 2 (13) | 4 (31%) | 0.364 |
Cavitations | 2 (7%) | 0 (0%) | 2 (15%) | 0.192 |
Pneumomediastinum | 7 (24%) | 2 (13%) | 5 (38%) | 0.192 |
Pneumothorax | 5 (17%) | 1 (6%) | 4 (31%) | 0.14 |
Emphysema | 6 (21) | 3 (27%) | 3 (38%) | 1.00 |
P/F (PaO2/FiO2) | < 0.001 | |||
< 100 (%) | 40 | 11 | 29 | |
100–200 (%) | 72 | 41 | 31 | |
> 200 (%) | 10 | 9 | 1 | |
`Respiratory support | 0.003 | |||
NIV (%) | 63 | 41 | 22 | |
IOT (%) | 39 | 13 | 26 |