Table 5 Characteristics and outcomes of retrieved trials for the outcome “Pericardial Effusion”
From: Cardiac complications in patients with COVID-19: a systematic review
Pericardial effusion | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Authors | Age (years) all patients | Age (years) treatment group | Age (years) control group | Sex M/F+ | Cardiological comorbidities (n° pts) | Other comorbidities (n° pts) | COVID-19 severity | Volume (n° pts or cases-controls) | Cardiac tamponade (n° pts or cases/controls) | Other no cardiac complications (n° pts) | Outcome (n° pts or cases- controls) Outcome (n° pts or cases-controls) |
Chen et al. [16] | 57.6 (44.9–70.3)§ | 56.1 ± 13.5 ° | 61.7 ± 9.6° | 36/18 | Hypertension (16) Diabetes (25) Coronary heart disease (6) | NA | Severe condition: Respiratory distress, RR > 30 acts/min or SpO2 < 93% at rest or P/F < 300 Critical condition if: Mechanical ventilation or shock or failure of other organs that requires monitoring and treatment in ICU | Not reported (1–5) | 0 | AKI (18) | NA |
Dabbagh et al. [18] | 63+ | NA | NA | 0/1 | Dilated cardiomyopathy (1) Chronic heart failure (1) | NA | NA | 800 ml+ (1) | 1 | NA | Discharge (1) |
Deng et al. [19] | 65 (49–70.8)§ | 56 (39–67)§ | 68 (57–77)§ | 57/55 | Hypertension (36) Diabetes (19) Coronary heart disease (15) Atrial fibrillation (4) | COPD (4) | Severe patients if: Respiratory distress and RR> 30 acts/min or SpO2 < 93% or P/F < 300 Critical patients if: Respiratory failure with ventilation mechanical or shock or multi-organ failure requiring hospitalization in ICU | 6.2 ± 1.1 mm° (3–19) | 0 | Mechanical ventilation (28) ECMO (3) | Death (14) Discharge (37) |
Dweck et al. [24] | 62 (52–71)§ | 64 (53–73)§ | 60 (51–69)§ | 844/365 | Hypertension (445) Diabetes (233) Ischemic heart disease (167) Heart failure (113) Valvular disease (80) | NA | Patients in critical care setting (ICU, coronary care unit, emergency room, cardiac catheter laboratory) | Not reported (11) | 11 | NA | NA |
Kunal et al. [32] | 51.2 ± 17.7° | 60.9 ± 15.1° | 47.9 ± 17.4° | 70/38 | Hypertension (41) Diabetes (35) Cardiovascular disease (14) Dyslipidemia (6) Heart failure (1) | COPD (6) | NA | Not reported (2) | 0 | Sepsis (25) ARDS (12) AKI (8) Diabetic ketoacidosis (3) Intracranial hemorrhage (1) | NA |