Should we use diastolic function parameters to determine preload responsiveness in cardiac surgery? A pilot study

Table 4 Areas under the receiver operating characteristic (ROC) curves generated for hemodynamic and echocardiographic parameters to predict changes in cardiac index

Variables	Area under the ROC curve	95% confidence interval	Threshold	Sensitivity (%)	Specificity (%)	P value
Hemodynamic
SVV (%)	0.6994	0.5486-0.8502	12	66.7	62.5	0.0096
PPV (%)	0.6343	0.4648-0.8038				0.1205
PCWP ratio a/v	0.5307	0.3603-0.7011				0.7240
Echocardiographic
EDA (cm²)	0.6917	0.5290-0.8544	14.3	75.0	70.3	0.0209
MV E/e′ ratio	0.5231	0.3628-0.6835				0.7772

EDA (cm²) end-diastolic area, MV E/e′ ratio E/e′ ratio of the mitral valve, PCWP ratio a/v ratio of the a/v wave of the pulmonary capillary wedge pressure tracing, PPV (%) pulse pressure variation, SVV (%) stroke volume variation measured with Flotrac

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